What is Constructive Biology™?
Constructive Biology™ is nothing less than a new paradigm for gene synthesis, a transformative approach that overcomes the problems and limitations of previous processes.
In the early 1970s, the first attempts to build genetic sequences were by gene splicing, copying and pasting together small segments of genetic code which produced a chimeric sequence that is now commonly known as recombinant DNA.
At the turn of the millennium, the sequencing of human and other genomes created demand for de novo synthesis of genes. This approach, called gene synthesis, was an improvement over gene splicing but proved to be slow, expensive, and limited in scope.
In late 2004, multiple breakthrough technologies gave rise to Constructive Biology™, a fundamentally new era of gene design and construction. With its proprietary BioFAB™ platform, Codon Devices designs and constructs engineered devices—such as full-length genes, operons, pathways, and ultimately genomes—quickly, accurately and at low cost.
Constructive Biology™ is ushering in a new era of biotechnology. The ability to engineer and construct biological devices on a massive scale is helping to drive breakthrough research across a wide range of interests that are vital to human endeavors, such as novel pharmaceuticals, improved vaccines, agricultural products, and biorefineries for the production of industrial chemicals and energy.